Current Projects

Our current projects are focused in understanding the role of environmental chemicals in development of childhood disease. 

Prenatal environmental exposure and child liver injury

Child liver injury and fatty liver disease are an important emerging public health problem. The goal of this project is to evaluate the impacts of a broad suite of prenatal environmental exposures on child liver injury.

ENVIRONMENTAL CHEMICAL EXPOSURE AND TYPE II DIABETES

Young onset type 2 diabetes is an important emerging public health problem. The goal of this project is to evaluate the impact of persistent organic chemicals, including organochlorine compounds, perfluoroalkyl substances, and brominated flame retardants, on susceptibility to type 2 diabetes in youth

EFFECTS OF DDE EXPOSURE ON METABOLIC IMPROVEMENT: BARIATRIC SURGERY STUDY DESIGN

Young onset type 2 diabetes is an important emerging public health problem. The goal of this project is to evaluate the impact of persistent organic chemicals, including organochlorine compounds, perfluoroalkyl substances, and brominated flame retardants, on susceptibility to type 2 diabetes in youth

Hepatotoxic effects of PFAS substances: a new epidemiological approach for studying NAFLD

The goal of this study is to examine the effects of widely used perfluoroalkyl substances (PFAS) on nonalcoholic fatty liver disease (NAFLD), using the gold standard of liver biopsies for disease diagnosis and liver-specific and plasma metabolomic measures to examine biological mechanisms linking PFAS to liver disease. We will examine this hypothesis in a novel study design using liver and plasma samples from obese adolescents undergoing bariatric surgery.